La missione del Children’s Brain Tumor Network, lanciata nel 2011 come Children’s Brain Tumor TissueConsorzio (CBTTC), deve fungere da multiistituzionale collaborativo consorzio di ricerca con un archivio di campioni biologici e dati accessibile al pubblico dedicato allo studio e al…

Abstract PMCID: PMC11183422 DOI: 10.1093/neuonc/noae064.436 Link: https://scholar.google.com/citations?view_op=view_citation&hl=en&user=70cz3rUAAAAJ&cstart=20&pagesize=80&citation_for_view=70cz3rUAAAAJ:eQOLeE2rZwMC INTRODUCTION Chemotherapy remains the cornerstone in case of incompletely resected pedatric Low Grade Glioma (pLGGs) and for recurrent tumors in unfavorable locations. Based on previous cisplatin etoposide regimen (INT Milan strategy), we tried to…

Abstract DOI: https://doi.org/10.1093/neuonc/noae064.318 Link: https://scholar.google.com/citations?view_op=view_citation&hl=en&user=70cz3rUAAAAJ&cstart=20&pagesize=80&citation_for_view=70cz3rUAAAAJ:qxL8FJ1GzNcC BACKGROUNDPediatric high-grade gliomas (pHGGs) comprise a very poor prognosis. Current treatment consists of maximal surgical resection followed by radiotherapy plus concomitant and adjuvant temozolomide (Stupp’s regimen). Despite innovative approaches, outcome remains dismal. Based on the…

Abstract PMID: 38681768 DOI: https://doi.org/10.3389/fendo.2024.1292025 Link: https://scholar.google.com/citations?view_op=view_citation&hl=en&user=70cz3rUAAAAJ&cstart=20&pagesize=80&citation_for_view=70cz3rUAAAAJ:_kc_bZDykSQC Background: Craniopharyngioma (CP), although slow growing and histologically benign, has high morbidity, mostly related to hypothalamus-pituitary dysfunction and electrolyte imbalance. Increased risk of vascular complications has been described. However, data are still poor, especially in…

Abstract PMID: 38621165 DOI: https://doi.org/10.1097/inf.0000000000004357 Link: https://scholar.google.com/citations?view_op=view_citation&hl=en&user=70cz3rUAAAAJ&cstart=20&pagesize=80&citation_for_view=70cz3rUAAAAJ:M3ejUd6NZC8C We read with great interest the manuscript written by Smiljkovic et al, 1 about intracranial suppurative complications of sinusitis in children. Acute bacterial sinusitis is common in children, and despite being mostly a disorder…

Abstract PMID: 38546282 DOI: https://doi.org/10.1080/02688697.2024.2333971 Link: https://scholar.google.com/citations?view_op=view_citation&hl=en&user=70cz3rUAAAAJ&cstart=20&pagesize=80&citation_for_view=70cz3rUAAAAJ:4TOpqqG69KYC Introduction: Skull base pathologies in the paediatric population are rare and require treatment by multiple qualified specialists. The endoscopic endonasal approach has revolutionized surgical treatment because it is less invasive than existing treatments.The goal of…

Abstract PMID: 37905828 DOI: https://doi.org/10.1227/ons.0000000000000973 Link: https://scholar.google.com/citations?view_op=view_citation&hl=en&user=70cz3rUAAAAJ&cstart=20&pagesize=80&citation_for_view=70cz3rUAAAAJ:ULOm3_A8WrAC To the Editor: We would like to thank you for the opportunity to respond to the issues raised in the letter by Dr Uribe-Cardenas 1 and to clarify aspects of our surgical technique in…

Abstract PMID: 38086219 DOI: https://doi.org/10.1016/j.eplepsyres.2023.107258 Link: https://scholar.google.com/citations?view_op=view_citation&hl=en&user=70cz3rUAAAAJ&cstart=20&pagesize=80&citation_for_view=70cz3rUAAAAJ:YOwf2qJgpHMC Background: Drug-resistant epilepsy is a common condition in patients with brain neoplasms. The pathogenesis of tumor-associated seizures is poorly understood. Among the possible pathogenetic mechanisms, the increase in glutamate concentration has been proposed. Glutamate transporters,…